Search results for "High myopia"

showing 10 items of 15 documents

Imbalance Between Oxidative Stress and Growth Factors in Human High Myopia.

2020

Este artículo se encuentra disponible en la siguiente URL: https://www.frontiersin.org/articles/10.3389/fphys.2020.00463/full Myopia is one of the commonest eye pathologies that could affect 2.56 billion people by 2020. Today high myopia is a leading cause of blindness worldwide due to associated ocular illness. Nevertheless, the cellular bases for these diseases to develop are unclear in many areas. We conducted a prospective study of oxidative stress and growth factors in human myopic and non myopic eyes in an attempt to increase our understanding of the underlying physiopathological conditions to adequately early diagnose, prevent and treat the retina problem that derives from myopia. Aq…

0301 basic medicinemedicine.medical_specialtygenetic structuresNitratos.PhysiologyVEGF receptorsCrecimiento - Factores.Affect (psychology)medicine.disease_causelcsh:Physiology03 medical and health sciencesElisa kit0302 clinical medicineCataractsPhysiology (medical)OphthalmologyMedicineoxidative stresstotal nitratesNitrates.HGFProspective cohort studyhigh myopiaDioptreOriginal ResearchEstrés oxidativo.biologylcsh:QP1-981business.industryMiopía.High myopiaTACGrowth factors.medicine.diseaseVEGFeye diseasesOxidative stress.030104 developmental biology030221 ophthalmology & optometrybiology.proteinsense organsbusinessMyopia.Oxidative stressFrontiers in physiology
researchProduct

Update and guidance on management of myopia : European Society of Ophthalmology in cooperation with International Myopia Institute

2021

The prevalence of myopia is increasing extensively worldwide. The number of people with myopia in 2020 is predicted to be 2.6 billion globally, which is expected to rise up to 4.9 billion by 2050, unless preventive actions and interventions are taken. The number of individuals with high myopia is also increasing substantially and pathological myopia is predicted to become the most common cause of irreversible vision impairment and blindness worldwide and also in Europe. These prevalence estimates indicate the importance of reducing the burden of myopia by means of myopia control interventions to prevent myopia onset and to slow down myopia progression. Due to the urgency of the situation, t…

0301 basic medicinemedicine.medical_specialtygenetic structuresmedicine.medical_treatmentatropinePsychological interventionReviewsorthokeratologylikinäköisyyspreventive medicineehkäisevä lääketiede03 medical and health sciences0302 clinical medicineOphthalmologynäkövammatEpidemiologyMyopiaPrevalenceMedicineHumansmyopiaPreventive healthcareBlindnessbusiness.industrypathologic myopiaPathological myopiaOrthokeratologyHigh myopiaTreatment optionsGeneral Medicinemedicine.diseasetime spent outdoorsmyopia reduction interventionsMyopia Degenerative/epidemiologyeye diseasesOphthalmology030104 developmental biologyMyopia Degenerativesilmätaudit030221 ophthalmology & optometryDisease Progressionsense organsbusinessOrthokeratologic Proceduresblindnesssokeus
researchProduct

Myopia and Cognitive Performance: Results From the Gutenberg Health Study.

2016

Purpose To analyze the association between myopia and cognitive performance. Methods A cohort of the population-based Gutenberg Health Study included 3819 eligible enrollees between 40 and 79 years. We used the Tower of London (TOL) test to assess cognitive performance. Myopia was defined as a spherical equivalent (SE) ≤ -0.5 diopters (D) via noncycloplegic autorefractometry. We conducted linear mixed models with the SE as the dependent variable and the age, sex, duration of education, and TOL score as covariates. Results Complete data were available for 3452 participants (90.4%). The mean TOL score was 14.0 ± 3.9 in the myopes versus 12.9 ± 4.0 in the nonmyopes (P < 0.001). The mean TOL sc…

AdultMaleComplete datamedicine.medical_specialtyTime Factorsgenetic structuresPopulationRefraction Ocular03 medical and health sciences0302 clinical medicineCognitionOphthalmologyGermanymedicineMyopiaPrevalenceHumansEffects of sleep deprivation on cognitive performanceProspective StudiesProspective cohort studyeducationDioptreAgededucation.field_of_studybusiness.industryHigh myopiaCognitionMiddle Agedeye diseasesPopulation SurveillanceCohort030221 ophthalmology & optometryOptometryEducational StatusFemalebusiness030217 neurology & neurosurgeryFollow-Up StudiesInvestigative ophthalmologyvisual science
researchProduct

Medium-term visual, refractive, and intraocular stability after implantation of a posterior chamber phakic intraocular lens to correct moderate to hi…

2011

To evaluate the medium-term refractive and visual outcomes and the complications after implantation of a silicone posterior chamber phakic intraocular lens (PC pIOL) for moderate to high myopia.Oftalmar, Medimar International Hospital, Alicante, Spain.Retrospective case series.Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, and intraocular pressure were evaluated during a medium-term follow-up. Postoperative complications were also studied.The study enrolled 35 eyes (mean preoperative spherical equivalent [SE] -10.25 diopters [D] ± 3.19 [SD]) of 20 patients with a mean age of 31.83 ± 8.87 years and a mean follow-up of 57.34 ± 9.24 months. The mean UDVA improved…

AdultMaleIntraocular pressuremedicine.medical_specialtyPhakic Intraocular LensesVisual acuitygenetic structuresVisual AcuityPhakic intraocular lensRefraction OcularMedium termYoung AdultPostoperative ComplicationsLens Implantation IntraocularOphthalmologyMedicineHumansDioptreIntraocular PressureRetrospective Studiesbusiness.industryHigh myopiaPosterior Eye SegmentMiddle AgedRefractioneye diseasesSensory SystemsPosterior chamber phakic intraocular lensOphthalmologyTreatment OutcomeMyopia DegenerativeSurgeryFemalemedicine.symptombusinessFollow-Up StudiesJournal of cataract and refractive surgery
researchProduct

Risk factors for high myopia: a 22‐year follow‐up study from childhood to adulthood

2018

PURPOSE To determine the effect of the definition of high myopia on its prevalence and risk factors for high myopia. METHODS A total of 240 myopic schoolchildren (119 boys and 121 girls) at the mean age of 10.9 years (range 8.8-12.8 years) were recruited to a randomized clinical trial of myopia treatment among children from 3rd- and 5th grades of school referred for an eye examination due to poor distant vision and having no previous spectacles. Clinical follow-ups, including refraction with cycloplegia, were conducted annually at 3 years [third follow-up here = clinical follow-up 1, (n = 237)], and thereafter twice at approximately 10-year intervals [clinical follow-ups 2 (n = 179) and 3, …

AdultMalePediatricsmedicine.medical_specialtyYounger ageAdolescentgenetic structuresRefraction Ocularlaw.inventionYoung Adult03 medical and health sciences0302 clinical medicineRandomized controlled trialRisk FactorslawSurveys and QuestionnairesMyopiaPrevalencemedicineHumansChildFinlandRetrospective Studiesmedicine.diagnostic_testbusiness.industryVision TestsFollow up studiesHigh myopiaCycloplegiaGeneral MedicineOdds ratioeye diseasesOphthalmologyEyeglassesEye examinationCohortDisease Progression030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryFollow-Up StudiesForecastingActa Ophthalmologica
researchProduct

Five-year functional outcomes and vault of -20 diopter myopic phakic intraocular lens implantation.

2015

Purpose To evaluate refractive and visual outcomes and complications associated with phakic intraocular lens (pIOL) implantation to correct high myopia. Settings Fernandez-Vega Ophthalmological Institute, Oviedo, Spain. Design Retrospective observational case series. Methods Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), refraction, vault, and adverse effects were evaluated after 5 years with Visian ICMV4 pIOL. Results Mean spherical equivalent (SE) dropped from −18.32 ± 2.37 diopters (D) preoperatively to −0.88 ± 0.52D 5 years postoperatively; 61% of eyes were within ±0.75 D of the target. The mean Snellen decimal CDVA and UDVA were 0.73 ± 0.23 and 0…

AdultMalePhakic Intraocular LensesVisual acuityAnterior subcapsular cataractDistance visual acuityBiometrygenetic structuresmedicine.medical_treatmentVisual AcuityPhakic intraocular lensRefraction OcularPostoperative ComplicationsLens Implantation IntraocularAnterior Eye SegmentmedicineMyopiaHumansDioptreRetrospective StudiesEfficacy indexbusiness.industryHigh myopiaCataract surgeryeye diseasesSensory SystemsOphthalmologyOptometrySurgeryFemalesense organsmedicine.symptombusinessTomography Optical CoherenceFollow-Up StudiesJournal of cataract and refractive surgery
researchProduct

Retinal Imaging through Phakic Iris-Claw IOL.

2014

AbstractBackground: Phakic anterior chamber iris-fixated IOL (PIOL) are established for the correction of high myopia. These patients require attention to macular pathologies. This study was to evaluate the quality of imaging through the PIOLs. Methods: 54 eyes of 31 myopic and hyperopic patients with Verisyse®, Verisyse toric®, and Veriflex® phakic iris-fixated IOL were included. Mean preoperative refraction was −11.0 D and +5.7 D, respectively; mean follow-up time was 7.4 years (5–11 years). A matched control group was formed without PIOL implantation. OCT scans were performed and evaluated qualitatively and quantitatively. Results: In 52 eyes of 31 patients (96%), a 3D-OCT image and fund…

AdultMalemedicine.medical_specialtyPhakic Intraocular Lensesgenetic structuresAnterior ChamberVisual AcuityIrisFoveal thicknessFundus (eye)Refraction OcularRetinaImaging Three-DimensionalLens Implantation IntraocularOphthalmologymedicineMyopiaHumansPhakic iolIris clawmedicine.diagnostic_testbusiness.industrySignificant differenceFundus photographyHigh myopiaGeneral MedicineMiddle Agedeye diseasesOphthalmologyHyperopiaRetinal imagingFemalesense organsbusinessTomography Optical CoherenceFollow-Up StudiesSeminars in ophthalmology
researchProduct

Behaviour of the phakic iris-claw intraocular lens (Artisan /Verisyse) during accommodation: an optical coherence biometry study.

2007

Purpose To evaluate variations in the position of the phakic iris claw lens (Artisan®, Verisyse®) and the natural crystalline lens during the accommodation process. Methods We measured changes in position of the iris claw lens and the crystalline lens during the accommodation using optical coherence biometry (AC Master®/Carl Zeiss Meditec, Germany) in 17 patients (28 eyes) with a phakic iris claw lens implanted for high myopia and/or myopic astigmatism. Accommodative effort was obtained using an internal optical target within the measuring device. Results There was a forward shift of the phakic iris claw lens with a mean of 70 μm (8–178 μm) of the optical path length (OPL). At the same time…

Adultmedicine.medical_specialtyPhakic Intraocular LensesMaterials scienceBiometrymedicine.medical_treatmentIrisIntraocular lensRefraction OcularMyopic astigmatism03 medical and health sciences0302 clinical medicineOpticsLens Implantation IntraocularAnterior Eye SegmentOphthalmologyLens CrystallinemedicineMyopiaHumansIris clawOptical path lengthbusiness.industryHigh myopiaAccommodation OcularAstigmatismGeneral MedicineMiddle AgedOphthalmologymedicine.anatomical_structureLens (anatomy)030221 ophthalmology & optometrybusinessAccommodation030217 neurology & neurosurgeryTomography Optical CoherenceCoherence (physics)Follow-Up StudiesEuropean journal of ophthalmology
researchProduct

Chromatic and achromatic visual fields in relation to choroidal thickness in patients with high myopia: A pilot study

2018

Purpose. - To analyse the relationship between the choroidal thickness and the visual perception of patients with high myopia but without retinal damage. Methods. - All patients underwent ophthalmic evaluation including a slit lamp examination and dilated ophthalmoscopy, subjective refraction, best corrected visual acuity, axial length, optical coherence tomography, contrast sensitivity function and sensitivity of the visual pathways. Results. - We included eleven eyes of subjects with high myopia. There are statistical correlations between choroidal thickness and almost all the contrast sensitivity values. The sensitivity of magnocellular and koniocellular pathways is the most affected, an…

Adultmedicine.medical_specialtyVisual perceptiongenetic structuresColorPilot ProjectsVisual systemSeverity of Illness IndexContrast SensitivityOphthalmoscopyYoung Adult03 medical and health sciences0302 clinical medicineOptical coherence tomographyOphthalmologyHigh myopiaMyopiamedicineHumansMotion perceptionContrast sensitivityColor Perception TestsColor Visionmedicine.diagnostic_testVisual pathwayChoroidbusiness.industryOrgan SizeMiddle AgedSubjective refractioneye diseasesVisual fieldOphthalmoscopyOphthalmologyKoniocellular cellChoroidal thickness030221 ophthalmology & optometrysense organsVisual FieldsbusinessVision fieldColor PerceptionTomography Optical Coherence030217 neurology & neurosurgery
researchProduct

Bilateral implantation of the Acri.LISA bifocal intraocular lens in myopic eyes.

2009

Purpose To asses visual quality after bilateral implantation of the Acri.LISA 366D intraocular lens (IOL) (Carl Zeiss Meditec) in patients with high and low–moderate myopia. Methods A total of 304 eyes of 152 patients had bilateral implantation of the Acri.LISA 366D IOL. The patients were divided into 2 groups: low–moderate myopia (IOL power from 15 to 20.5 D) and high myopia (IOL power from 0 to 14.5 D). Monocular and binocular best-corrected distance visual acuity (BCVA) and best distance-corrected near visual acuity (BCNVA), binocular best distance-corrected intermediate visual acuity (BCIVA), and distance contrast sensitivity (OS) under photopic (85 cd/m2) and mesopic (5 cd/m2) conditio…

MaleVisual acuitygenetic structuresMesopic visionmedicine.medical_treatmentVisual AcuityIntraocular lensExtractionFunctional LateralityTratamiento médico0302 clinical medicineLens Implantation IntraocularMyopiaContrast (vision)MedicineRetinal-Detachmentmedia_commonVistaLenses IntraocularVision BinocularDistanceHigh myopiaRetinal detachmentGeneral MedicineMiddle AgedQualityTreatment OutcomeOftalmologíaFemalemedicine.symptomPhotopic visionRiskmedia_common.quotation_subjectProsthesis DesignContrast Sensitivity03 medical and health sciencesHumansMonocularPhacoemulsificationbusiness.industryMultifocal Iolmedicine.diseaseeye diseasesVisual PerformanceOphthalmology030221 ophthalmology & optometryOptometrysense organsbusiness030217 neurology & neurosurgeryEuropean journal of ophthalmology
researchProduct